Safety Information

Do you have gallstones?

Learn about nonsurgical treatment.

Gallstones are a chronic medical condition.

They tend to reoccur unless the risk factors are changed.

Up to half (50%) of patients whose stones dissolve on bile acid therapy have stones return within 5 years when they stop therapy.1

Treatment with Reltone

Reltone is approved for dissolving gallstone, avoiding the need for surgery in select patients.

A nonsurgical option for some patients

Reltone (ursodiol capsule, USP) is a prescription medicine that is taken by mouth. The active ingredient in Reltone, ursodiol, is also naturally made by the liver. You may be a candidate for Reltone if you have gallstones, even with mild or no symptoms.


Reltone is proven therapy for dissolving certain gallstones.

Reltone & Gallstone Dissolution

Reltone may be an option if:

The gallstone is smaller than 20mm in diameter, noncalcified, not visible with X-ray (radiolucent)

You do not choose to have surgery
Reltone is not an option if:
You are allergic to bile acids
You have medical reasons to have gallbladder surgery

The gallstone is larger than 20mm in diameter, calcified, visible with X-ray (radiopaque), made of bile pigment stone that is invisible with X-ray (radiolucent)

Nonsurgical Treatment Time1

In clinical trials, ursodiol completely dissolved the stone in more than 80% of patients with gallstones up to 5mm in diameter.

In general, studies showed that gallstones were completely dissolved in about 30% of patients who:

Had stones that were noncalcified
Had stones less than 20mm in diameter
Were treated for up to 2 years

Ready to Protect Your Gallbladder?

How to Ask for Reltone